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HYBRID FORMULATION OF RESPONSIVE POLYMERIC NANOCARRIERS FOR THERAPEUTIC AND DIAGNOSTIC DELIVERY
HYBRID FORMULATION OF RESPONSIVE POLYMERIC NANOCARRIERS FOR THERAPEUTIC AND DIAGNOSTIC DELIVERY
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机译:用于治疗性和诊断性递送的反应性聚合物纳米载体的混合配方
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摘要
The present invention provides a nanocomplex comprising at least one agent and a nanocarrier. The agent is bound to the nanocarrier. The nanocarrier comprises at least one cationic polymer responsive to a stimulus, at least one anionic polymer and at least one lipid. The agent is capable of being released from the nanocarrier upon exposure to the stimulus. The released agent is active. The nanocomplex may be used to deliver the agent into cells, in which the agent may be released from the nanocarrier upon exposure of the cells to the stimulus.
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