首页> 外国专利> Methods of treating castration-resistant prostate cancer with glucocorticoid receptor antagonists after anticancer therapy

Methods of treating castration-resistant prostate cancer with glucocorticoid receptor antagonists after anticancer therapy

机译:抗癌治疗后用糖皮质激素受体拮抗剂治疗去势抵抗性前列腺癌的方法

摘要

Embodiments of the invention are directed to the treatment of subjects with prostate cancer, in particular those with castration resistant prostate cancer, with glucocorticoid receptor antagonists. The prostate cancer may be one that has become resistant to androgen deprivation therapy, for example, by increase in glucocorticoid receptor expression and/or activity.
机译:本发明的实施方案涉及用糖皮质激素受体拮抗剂治疗患有前列腺癌,特别是具有去势抵抗性前列腺癌的受试者。前列腺癌可以是例如通过增加糖皮质激素受体表达和/或活性而对雄激素剥夺疗法具有抗性的癌症。

著录项

  • 公开/公告号US10729699B2

    专利类型

  • 公开/公告日2020-08-04

    原文格式PDF

  • 申请/专利权人 THE UNIVERSITY OF CHICAGO;

    申请/专利号US201916374157

  • 发明设计人 RUSSELL Z. SZMULEWITZ;SUZANNE D. CONZEN;

    申请日2019-04-03

  • 分类号A61K31/567;A61K31/4166;A61K31/437;A61K31/569;A61K31/573;A61K45/06;A61N5/10;

  • 国家 US

  • 入库时间 2022-08-21 11:27:48

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