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Microfluidic chip, apparatus for enriching cells and method for enriching cells in a microfluidic chip

机译:微流体芯片,用于富集细胞的设备和用于富集微流体芯片中的细胞的方法

摘要

In accordance with an embodiment, a microfluidic chip including a first cells enrichment system and a second cells enrichment system is provided. Channel layouts of the first and the second cells enrichment systems are symmetric with respect to a reflection plane vertical to the microfluidic chip. Each of the first the second cells enrichment systems includes a first fluid channel, a second fluid channel, a sample channel, an inlet channel, and a filtration chamber. The sample channel of the first cells enrichment system has a first inner wall and a first outer wall. The sample channel of the second cells enrichment system has a second inner wall and a second outer wall. The first outer wall and the second outer wall are both far from the reflection plane. A distance between the first outer wall and the second outer wall is in the range from about 10 μm to about 1 cm.
机译:根据一个实施例,提供了一种包括第一细胞富集系统和第二细胞富集系统的微流体芯片。第一细胞富集系统和第二细胞富集系统的通道布局相对于垂直于微流体芯片的反射平面对称。每个第一第二细胞富集系统均包括第一流体通道,第二流体通道,样品通道,入口通道和过滤室。第一细胞富集系统的样品通道具有第一内壁和第一外壁。第二细胞富集系统的样品通道具有第二内壁和第二外壁。第一外壁和第二外壁均远离反射平面。第一外壁和第二外壁之间的距离在约10μm至约1cm的范围内。

著录项

  • 公开/公告号US10730049B2

    专利类型

  • 公开/公告日2020-08-04

    原文格式PDF

  • 申请/专利权人 MICAREO TAIWAN CO. LTD.;

    申请/专利号US201815975794

  • 发明设计人 HUI-MIN YU;WEN-FENG CHUNG;JUI-LIN CHEN;

    申请日2018-05-10

  • 分类号B01L3;C12M3;C12M1/02;G01N15/10;G01N15/14;

  • 国家 US

  • 入库时间 2022-08-21 11:27:46

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