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Thermoreversible hydrogels from the arrested phase separation of elastin-like polypeptides
Thermoreversible hydrogels from the arrested phase separation of elastin-like polypeptides
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机译:弹性蛋白样多肽阻滞相分离的热可逆水凝胶
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摘要
Elastin-like polypeptides (ELPs) form hydrogels upon heating. The polypeptides can comprise the generic sequence (XPAVG)n (SEQ ID NO: 4), wherein independently for each occurrence X can be any one of a number of different natural or unnatural amino acids, and n is chosen to determine the size of the protein. Hydrogels comprising the polypeptides have mechanical properties, including elastic modulus and fracture toughness, required for load-bearing applications.
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机译:弹性蛋白样多肽(ELP)在加热时形成水凝胶。所述多肽可以包含通用序列(XPAVG)n n Sub>(SEQ ID NO:4),其中对于每次出现,X可以独立地为许多不同的天然或非天然氨基酸中的任何一个,并且n为选择以确定蛋白质的大小。包含多肽的水凝胶具有承载应用所需的机械性能,包括弹性模量和断裂韧性。
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