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Peptide having anticancer activity, and pharmaceutical composition and dietary supplement composition for preventing and treating cancer, both of which contain same as active ingredient

机译:具有抗癌活性的肽,用于预防和治疗癌症的药物组合物和饮食补充剂组合物,两者均含有相同的活性成分

摘要

A peptide binding to transcription factor CP2c, having an activity of preventing and treating cancer and represented by SEQ ID NO: 1: Asn-Tyr-Pro-Gln-Arg-Pro, and a pharmaceutical composition and a dietary supplement composition for preventing and treating cancer, both of which contain the same as an active ingredient are disclosed. When cancer cells are treated with the peptide and the pharmaceutical composition containing the same, the peptide can specifically bind to CP2c by passing, with very high stability, through the cell membrane and can inhibit the DNA binding ability of CP2c, thereby disturbing CP2c-mediated cancer cell-specific transcriptional activity through the inhibition of CP2c activity. Thus, the peptide and pharmaceutical composition containing the same can be effectively used for specifically treating only cancer cells and can be utilized for cancer prevention and as a dietary supplement additive therefor.
机译:具有SEQ ID NO:1所示的具有预防和治疗癌症的活性的与转录因子CP2c结合的肽,以及用于预防和治疗的药物组合物和饮食补充剂组合物公开了两者都含有与活性成分相同的癌症。当用该肽和含有该肽的药物组合物治疗癌细胞时,该肽可以通过以非常高的稳定性穿过细胞膜而特异性结合CP2c,并且可以抑制CP2c的DNA结合能力,从而干扰CP2c介导的通过抑制CP2c活性,癌细胞具有特定的转录活性。因此,该肽和含有该肽的药物组合物可以有效地仅用于特异性地治疗癌细胞,并且可以用于癌症预防和作为其饮食补充添加剂。

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