首页> 外国专利> PEPTIDE HAVING ANTICANCER ACTIVITY, AND PHARMACEUTICAL COMPOSITION AND DIETARY SUPPLEMENT COMPOSITION FOR PREVENTING AND TREATING CANCER, BOTH OF WHICH CONTAIN SAME AS ACTIVE INGREDIENT

PEPTIDE HAVING ANTICANCER ACTIVITY, AND PHARMACEUTICAL COMPOSITION AND DIETARY SUPPLEMENT COMPOSITION FOR PREVENTING AND TREATING CANCER, BOTH OF WHICH CONTAIN SAME AS ACTIVE INGREDIENT

机译:具有抗癌活性的肽,预防和治疗癌症的药物成分和饮食补充成分,两者均属于有效成分

摘要

The present invention relates to a peptide having an anticancer activity, and a pharmaceutical composition and a dietary supplement composition for preventing and treating cancer, both of which contain the same as an active ingredient and, more specifically, to a peptide binding to transcription factor CP2c, having an activity of preventing and treating cancer and represented by SEQ ID NO: 1, and a pharmaceutical composition and a dietary supplement composition for preventing and treating cancer, both of which contain the same as an active ingredient. SEQ ID NO: 1 Asn-Tyr-Pro-Gln-Arg-Pro When cancer cells are treated with the peptide and the pharmaceutical composition containing the same, according to the present invention, the peptide can specifically bind to CP2c by passing, with very high stability, through the cell membrane and can inhibit the DNA binding ability of CP2c, thereby disturbing CP2c-mediated cancer cell-specific transcriptional activity through the inhibition of CP2c activity, and thus the present invention can be effectively used for specifically treating only cancer cells, and can be utilized for cancer prevention and as a dietary supplement additive therefor.
机译:本发明涉及具有抗癌活性的肽,以及用于预防和治疗癌症的药物组合物和饮食补充剂组合物,两者均包含与活性成分相同的肽,更具体地,涉及与转录因子CP2c结合的肽。具有预防和治疗癌症的活性并由SEQ ID NO:1表示,以及用于预防和治疗癌症的药物组合物和饮食补充剂组合物,两者均包含相同的活性成分。 Asn-Tyr-Pro-Gln-Arg-Pro根据本发明,当用该肽和含有该肽的药物组合物治疗癌细胞时,该肽可以通过与多肽特异性结合。通过细胞膜具有非常高的稳定性,并且可以抑制CP2c的DNA结合能力,从而通过抑制CP2c的活性来干扰CP2c介导的癌细胞特异性转录活性,因此本发明仅可有效地用于特异性治疗癌细胞,并且可以用于癌症预防,并作为其膳食补充剂。

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