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IMMUNOPOTENTIATOR, FOOT-AND-MOUTH DISEASE INACTIVATED VACCINE AND PREPARATION METHOD THEREOF

机译:免疫增强剂,口蹄疫失活疫苗及其制备方法

摘要

A compound immunopotentiator and application thereof relates to the preparation of the compound immunopotentiator and the application thereof in a foot-and-mouth disease vaccine of pigs. The foot-and-mouth disease vaccine of pigs is taken as a research subject, and on this basis, several immunopotentiators having obvious immunopotentiating effects are selected for the compound immunopotentiator, and an antigen/vaccine is mixed with the immunopotentiator to prepare a vaccine-immunized pig. After immunizing the vaccine containing the compound immunopotentiator, a window period for antibody production can be significantly shortened to 7 days; a LPB-ELISA antibody titer is significantly improved, and an antibody pass rate is significantly increased; an immune protection period is also significantly extended, at least up to 7 months; and the compound immunopotentiator is safe, and has no obvious side effects of immunity.
机译:化合物免疫增强剂及其应用涉及该化合物免疫增强剂的制备及其在猪口蹄疫疫苗中的应用。以猪的口蹄疫疫苗为研究对象,在此基础上,选择几种具有明显免疫增强作用的免疫增强剂作为复合免疫增强剂,并将抗原/疫苗与免疫增强剂混合制备疫苗。免疫猪。免疫含有复合免疫增强剂的疫苗后,抗体产生的窗口期可以大大缩短至7天; LPB-ELISA抗体效价显着提高,抗体通过率显着提高;免疫保护期也显着延长,至少长达7个月;本发明的复合免疫增强剂安全,无明显的免疫副作用。

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