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Materials and methods for rapid and sensitive detection of small-molecule targets
Materials and methods for rapid and sensitive detection of small-molecule targets
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机译:快速灵敏地检测小分子靶标的材料和方法
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摘要
The subject invention provides methods, assays and products for detecting small-molecules in a sample, in particular, in both clinical and field settings. The method for detecting a small-molecule target in a sample comprises providing a sample, contacting the sample with an aptamer-based sensor selective for the small-molecule target, and sensitively and rapidly detecting the small-molecule target in the sample. Specifically, the method utilizes EATR-amplified small-molecule sensors based on cooperative binding split aptamers (CBSAs).
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