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BIOMARKERS FOR PREDICTING PROGNOSIS OF KIDNEY DISEASE

机译:预测肾脏疾病预后的生物标志物

摘要

A kit for diagnosing a renal disease or predicting prognosis of the renal disease from urine includes a binding molecule specifically bound to cMet protein contained in the urine. When a level of cMet protein in urine is higher than a normal group, this condition is diagnosed as the renal disease or predicted to have poor prognosis thereof. A screening method of a substance for treatment of renal disease includes first-measuring a level of cMet protein in urine of an object, injecting a sample to be analyzed into the object, and second-measuring the level of cMet protein in urine of the object. When the level of cMet protein in the second-measuring is lower than the level of cMet protein in the first-measuring, the sample to be analyzed is the substance for treatment of renal disease.
机译:用于从肾脏诊断肾脏疾病或预测肾脏疾病预后的试剂盒包括与尿中包含的cMet蛋白特异性结合的结合分子。当尿液中的cMet蛋白水平高于正常组时,该病被诊断为肾脏疾病或预后不良。用于治疗肾脏疾病的物质的筛选方法包括:首先测量对象尿液中的cMet蛋白水平,将待分析的样品注入对象体内,然后测量对象尿液中的cMet蛋白水平。 。当第二次测量中的cMet蛋白水平低于第一次测量中的cMet蛋白水平时,要分析的样品就是治疗肾脏疾病的物质。

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