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Prodrugs of a JAK Inhibitor Compound for Treatment of Gastrointestinal Inflammatory Disease

机译:JAK抑制剂化合物的前药治疗胃肠道炎症性疾病

摘要

The invention provides compounds which are prodrugs of a JAK inhibitor agent for the targeted delivery of the JAK inhibitor to the gastrointestinal tract of a mammal. The invention also provides pharmaceutical compositions comprising the compounds, methods of using the compounds to treat gastrointestinal inflammatory diseases, and processes and intermediates useful for preparing the compounds.
机译:本发明提供了化合物,其为JAK抑制剂的前药,用于将JAK抑制剂靶向递送至哺乳动物的胃肠道。本发明还提供了包含所述化合物的药物组合物,使用所述化合物治疗胃肠炎性疾病的方法,以及用于制备所述化合物的方法和中间体。

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