Novel Route of Nasal Administration of Aripiprazole for Treatment of Eating Disorders

摘要

The use of a novel route of administration of aripiprazole for treatment of an eating disorder. Specifically, the use of an intranasal route of administration of aripiprazole for treatment of an eating disorder such as anorexia nervosa, atypical anorexia nervosa, bulimia nervosa, binge-eating disorder, purging disorder, or any combination of multiple types of eating disorders, as well as any syndrome disease such as night eating syndrome, carcinoid syndrome, or serotonin syndrome or any diseases or symptoms comorbid with an eating disorder. This intranasal route of administration will most likely reach the brain via the single epithelial cell layers of the nose to blood vessels to the cerebrospinal fluid neighboring the olfactory bulbs and finally into the nervous system where it may produce both local or systemic effects. This route may treat neurotransmitter imbalances, altered eating behaviors, or comorbid symptoms or diseases associated with an eating disorder including treatment and compliance.