Ultra-sensitive and Universal Species Detection Pipeline for Next Generation Sequencing Data

摘要

A presumption-free pipeline is provided that employs experimental and analytic modules to profile samples, including clinical samples, regardless of the complexity and abundance. The experimental and analytic modules can work independently of each other if the user so desired. The experimental module for ultra-sensitive DNA/RNA extraction and sequencing can be used to extract information from any samples to feed into analytical pipelines chosen by the user. Alternatively, the analytic module for universal species detection can be fed with data generated with other experimental pipelines and different sequencing platforms.