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Silencing of HNF4A-P2 Isoforms with siRNA to Improve Hepatocyte Function in Liver Failure
Silencing of HNF4A-P2 Isoforms with siRNA to Improve Hepatocyte Function in Liver Failure
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机译:用siRNA沉默HNF4A-P2亚型以改善肝功能衰竭中的肝细胞功能
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摘要
Provided herein are antisense agents for knocking down, inhibiting, or silencing expression of an HNF4α-P2 isoform mRNA in a cell or a patient. Also provided are methods of knocking down, inhibiting, or silencing expression of an HNF4α-P2 isoform mRNA in a cell or a patient and methods of treating a patient with liver disease, liver damage, liver inflammation, or liver failure, such as acute liver failure, ALD, AH, or ACLF.
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