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ATTENUATION OF NEUROPATHIC PAIN AFTER SPINAL CORD INJURY

机译:脊髓损伤后神经病理性疼痛的减弱

摘要

Methods for treating neuropathic pain caused by a traumatic spinal cord injury are described. A method comprising administering an effective amount of flubendazole, an α-tubulin acetylation inhibitor, an endosomal NR1 and pERK1/2 inhibitor, a mitochondrial cyclin b1 inhibitor, a microtubule destabilizing drug, or combinations thereof to the patient suffering from the traumatic spinal cord injury. Also described is a method for preventing neuropathic pain in a patient with a spinal cord injury at risk for developing neuropathic pain comprising administering administrating an effective amount of flubendazole to a patient with the spinal cord injury at risk of developing neuropathic pain.
机译:描述了治疗由脊髓损伤引起的神经性疼痛的方法。一种方法,该方法包括向遭受创伤性脊髓损伤的患者施用有效量的氟苯达唑,α-微管蛋白乙酰化抑制剂,内体NR1和pERK1 / 2抑制剂,线粒体细胞周期蛋白b1抑制剂,微管去稳定剂或其组合。 。还描述了一种在患有神经病性疼痛风险的脊髓损伤患者中预防神经性疼痛的方法,该方法包括对患有神经病性疼痛风险的脊髓损伤患者给予有效量的氟苯达唑。

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