ALTERING EXPRESSION LEVEL OF GLUTATHIONE S-TRANSFERASE GENES BY TREATING A HUMAN SUBJECT WITH A NITROXIDE

摘要

A method of treatment is disclosed. The method comprises administering to a human subject, known to have decreased glutathione activity, an effective amount of a nitroxide antioxidant, wherein the nitroxide antioxidant increases an expression level of one or more genes encoding glutathione S-transferase enzymes, thereby increasing glutathione activity.