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COMPOSITION AND KIT FOR DIFFERENTIATING CANCER ASSOCIATED FIBROBLASTS INTO MACROPHAGES, AND METHOD OF USING THE SAME
COMPOSITION AND KIT FOR DIFFERENTIATING CANCER ASSOCIATED FIBROBLASTS INTO MACROPHAGES, AND METHOD OF USING THE SAME
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机译:用于将癌相关成纤维细胞分化为巨噬细胞的组合物和试剂盒,及其使用方法
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摘要
Provided are a composition and a kit for reprogramming cancer associated fibroblasts (CAFs) into macrophages, and a method of using the same. According to a method of reprogramming CAFs according to an aspect, macrophages may be prepared with a high yield in a short period of time, and the tumor microenvironment may be suppressed and macrophages produced by reprogramming CAF may elimininate cancer cells. Therefore, the macrophages may be usefully applied as an anticancer agent or an anticancer adjuvant.
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