Composition and kit for differentiating cancer associated fibroblasts to macrophage and method using the same

摘要

It relates to a composition for differentiation of cancer-associated fibroblasts into macrophages, a kit, and a method using the same. According to the cancer-associated fibroblast reprogramming method according to one aspect, macrophages can be produced with a high yield within a short period of time, and macrophages that not only suppress the tumor microenvironment by removing cancer-associated fibroblasts, but also kill cancer cells. Because it can be differentiated into, it can be usefully used as an anticancer agent or anticancer adjuvant.