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TYPE 1 INTERFERON RECEPTOR ANTAGONISTS FOR USE IN METHODS OF TREATING TUBERCULOSIS AND OTHER INFECTIOUS DISEASES
TYPE 1 INTERFERON RECEPTOR ANTAGONISTS FOR USE IN METHODS OF TREATING TUBERCULOSIS AND OTHER INFECTIOUS DISEASES
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机译:1型干扰素受体拮抗剂,用于治疗结核病和其他感染性疾病
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摘要
The present invention relates to the use of type 1 interferon receptor antagonists that specifically bind IFNAR1 and/or IFNAR2 and inhibit type 1 IFNs signalling in methods of treating tuberculosis and other infectious diseases, in which type 1 interferon signalling has been found to be deleterious. Infectious diseases that can be treated according to the present invention include tuberculosis and leishmaniasis.
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