首页> 外国专利> COMPOSITION FOR PREVENTING OR TREATING LIVER FIBROSIS, CONTAINING EXOSOME OR EXOSOME-DERIVED RIBONUCLEIC ACID

COMPOSITION FOR PREVENTING OR TREATING LIVER FIBROSIS, CONTAINING EXOSOME OR EXOSOME-DERIVED RIBONUCLEIC ACID

机译:预防或治疗肝纤维化,含有外来或外来的核糖核酸的组合物

摘要

The present invention relates to a composition or cell therapeutic agent for preventing or treating liver fibrosis, containing an exosome or exosome-derived ribonucleic acid. The exosome or ribonucleic acid derived therefrom, of the present invention, has effects of inhibiting activities of hepatic stellate cells and Kupffer cells and reducing the expression of α-SMA and inhibits the progression of liver fibrosis by inhibiting the deposition of collagen, thereby being effectively usable as a cell therapeutic agent for the prevention or treatment of liver fibrosis.
机译:本发明涉及用于预防或治疗肝纤维化的组合物或细胞治疗剂,其包含外泌体或来自外泌体的核糖核酸。本发明衍生的外来体或核糖核酸具有抑制肝星状细胞和库普弗细胞的活性并降低α-SMA表达的作用,并通过抑制胶原蛋白的沉积来抑制肝纤维化的进展,从而有效地发挥作用。可用作预防或治疗肝纤维化的细胞治疗剂。

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