首页> 外国专利> USE OF A SOLID FRACTION SENSOR TO EVALUATE A SOLID FRACTION OF A TARGET PHARMACEUTICAL SAMPLE AND SOLID FRACTION SENSOR

USE OF A SOLID FRACTION SENSOR TO EVALUATE A SOLID FRACTION OF A TARGET PHARMACEUTICAL SAMPLE AND SOLID FRACTION SENSOR

机译:使用固体分数传感器评估目标药物样品和固体分数传感器的固体分数

摘要

For the use of a solid fraction sensor (17) to evaluate a solid fraction of a target pharmaceutical sample (4, 10) the solid fraction sensor (17) has a first conductor element (5), a second conductor element (7), an operation space (15) and an energy source (13) arranged to generate an electric field in the operation space (15) by means of the first conductor element (5) and the second conductor element (7), comprising positioning the target pharmaceutical sample (4, 10) in the operation space (15) of the solid fraction sensor (17), determining a capacitance between the first and second conductor element (5, 7) with the target pharmaceutical sample (4, 10) located in the operation space (15), and converting the determined capacitance together with information about a composition of a reference pharmaceutical sample having the essentially same dielectric properties as the target pharmaceutical sample (4, 10) and about a thickness of the reference pharmaceutical sample (4, 10) into a solid fraction of the target pharmaceutical sample (4, 10).
机译:对于使用固体分数传感器( 17 )评估目标药物样品( 4,10 )的固体分数,使用固体分数传感器( 17 < / B>)具有一个第一导体元素( 5 ),一个第二导体元素( 7 ),一个操作空间( 15 )和一个能源( 13 )布置为通过第一导体元件( 5 )在操作空间( 15 )中产生电场,并且第二导体元件( 7 ),包括将目标药物样品( 4、10 )放置在固体的操作空间( 15 )中分数传感器( 17 ),确定目标药物样品( 4、10 )在第一和第二导体元件( 5、7 )之间的电容>)放在操作空间( 15 )中,然后将确定的电容与有关具有与targ基本相同的介电特性的参比药物样品的组成信息一起转换药物样品( 4,10 )和参考药物样品( 4,10 )的厚度约等于目标药物样品( 4 ,10 )。

著录项

  • 公开/公告号US2020217811A1

    专利类型

  • 公开/公告日2020-07-09

    原文格式PDF

  • 申请/专利权人 HOFFMANN-LA ROCHE INC.;

    申请/专利号US201816648806

  • 发明设计人 JURAJ SIBIK;PASCAL CHALUS;

    申请日2018-09-21

  • 分类号G01N27/22;G01N33/15;

  • 国家 US

  • 入库时间 2022-08-21 11:20:21

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