The invention relates to the treatment of stroke using neural stem cells. In particular, the invention relates to functional improvements in stroke patients following treatment with CTX0E03 neural stem cells. In one aspect, the invention provides neural stem cells for use in a method of treating ischemic stroke, wherein a single dose of the cells is administered into the brain of a stroke patient having a modified NIHSS Motor Arm Score of 2 or 3, wherein the treatment improves motor function and alleviates disability within six months as determined by an increase of total ARAT score and/or a reduction in mRS of at least one category.
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