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Folate-conjugated molecules for delivery of toxic small molecule inhibitors to cancer cells and methods of use
Folate-conjugated molecules for delivery of toxic small molecule inhibitors to cancer cells and methods of use
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机译:叶酸偶联分子,用于向癌细胞输送有毒的小分子抑制剂及其使用方法
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摘要
The invention relates to novel derivatives of thapsigargin that are chemically modified with a group that targets a cell surface-expressed receptor, and pharmaceutical preparations thereof. The invention further relates to methods of treating diseases such as cancer using the compounds of the invention.
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