首页>
外国专利>
Regulation of Gene Expression by Aptamer-Mediated Accessibility of Polyadenylation Signals
Regulation of Gene Expression by Aptamer-Mediated Accessibility of Polyadenylation Signals
展开▼
机译:适体介导的聚腺苷酸化信号对基因表达的调控。
展开▼
页面导航
摘要
著录项
相似文献
摘要
The invention provides polynucleotide constructs for the regulation of gene expression by aptamer-based modulation of the accessibility of one or more polyadenylation signals and methods of using the constructs to regulate gene expression in response to the presence or absence of a ligand that binds the aptamer. The polynucleotide construct contains a riboswitch comprising an aptamer and an effector stem loop, wherein the effector stem loop comprises a polyadenylation signal sequence.
展开▼