The disclosure relates to a method and an imaging device for generating a new roadmap image of a target object. For the method, a first subtraction image is generated from a first mask image and a contrast agent image of the target object. A parameter value of a parameter of the imaging device that affects the acquisition of images by the device is then changed. A third mask image of the target object is acquired automatically by the imaging device using the changed parameter value. From a second examination image subsequently acquired using the changed parameter value, a third subtraction image is generated by subtraction of the third mask image. The new roadmap image is generated using the first subtraction image and the third subtraction image.
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