methods of modulating the alkaloid content and the content of a tobacco-specific nitrosamine (tsna), use of at least one nic1 erf gene, method of producing a plant, modified plant, plant propagation material, use of a plant, harvested leaf of a plant, processed leaf, cured tobacco material, tobacco mixture, tobacco industry product, tobacco product, use of a tobacco cell, fuel smoke article, use of a nucleotide sequence, mutant of a plant, progeny or seed

摘要

the present invention provides a method of modulating the alkaloid content of a plant (e.g., a tobacco plant), the method comprising modifying said plant by modulating the activity or expression of at least one nic1 erf gene. the present invention also provides the use of at least one nic1 erf gene for modulating the alkaloid content of a plant, as well as tobacco cells, plants, plant propagating materials, harvested leaves, processed tobacco or tobacco products obtainable accordingly with the invention.