ANTIVIRAL AGENT 1S- (1ALFA, 3ALFA, 4BETA) - 2-AMINO-1,9-DIIDRO-9- 4-HYDROXY-3- (HYDROXIMETHYL) -2-METHYLENOCYCLOPENTILE -6H-PURIN-6-ONA

摘要

the present invention relates to processes for preparing the antiviral agent entecavir. a resin adsorption process for the isolation and purification of entecavir is also disclosed. several intermediates useful in the preparation of entecavir are also disclosed.