selective nlrp3 inflammasome inhibitors

摘要

the present invention relates to the compounds of formula (i): (i); and its pharmaceutically acceptable salts, pharmaceutical compositions, methods of use, and methods for their preparation. the compounds described herein are useful for inhibiting cytokine maturation of the il-1 family by inhibiting inflammasomes and can be used to treat disorders in which inflammasome activity is implicated, such as autoinflammatory or autoimmune diseases and cancers.