use of staurosporine derivatives as inhibitors of tyrosine kinase flt3 receptor activity in the treatment of acute myeloid leukemia and high-risk myelodysplastic syndromes

摘要

"staurosporine derivatives as inhibitors of tyrosine kinase flt3 receptor activity". the present invention relates to the use of staurosporine derivatives for the preparation of a drug for the treatment of diseases involving the unregulated activity of flt3 tyrosine kinase receptors, especially for the curative and / or prophylactic treatment of leukemias and myelodysplastic syndromes, and to a method of treating diseases involving the unregulated activity of flt3 tyrosine kinase receptors.