首页> 外国专利> THYENOPYRIDONE DERIVATIVES AS AMP-ACTIVATED KINASE PROTEIN ACTIVATORS (AMPK), THEIR USES, THEIR PREPARATION PROCESS AND ITS INTERMEDIATES, AND MEDICINES

THYENOPYRIDONE DERIVATIVES AS AMP-ACTIVATED KINASE PROTEIN ACTIVATORS (AMPK), THEIR USES, THEIR PREPARATION PROCESS AND ITS INTERMEDIATES, AND MEDICINES

机译:乙酰吡啶酮衍生物作为AMP活化的激酶蛋白活化剂(AMPK),其用途,其制备过程及其中间体和药物

摘要

thienopyridinone derivatives as activators of amp activated protein kinase (ampk). the present invention relates to compounds of formula (i) in which r1, r2 and b1, b2 are as defined in claim 1, including pharmaceutical compositions thereof and for their use in the treatment and / or prevention of diseases and disorders modulated by amp agonists. the invention also relates to intermediates and a method of preparing compounds of formula (i).
机译:噻吩并吡啶酮衍生物作为amp活化蛋白激酶(ampk)的激活剂。本发明涉及式(i)的化合物,其中r1,r2和b1,b2如权利要求1所定义,包括其药物组合物及其在治疗和/或预防由安培激动剂调节的疾病和病症中的用途。本发明还涉及中间体和制备式(i)化合物的方法。

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