首页> 外国专利> method for treating infections with immune-mediated dengue fever and antibody-dependent intensification of infections with dengue fever, including hemorrhagic fever and dengue shock syndrome

method for treating infections with immune-mediated dengue fever and antibody-dependent intensification of infections with dengue fever, including hemorrhagic fever and dengue shock syndrome

机译:免疫介导的登革热感染的治疗方法以及包括出血热和登革热休克综合征在内的登革热感染的抗体依赖性增强

摘要

composition comprising polypeptide and use of said polypeptide in inhibiting the formation of immunocomplex associated with viral infection. polypeptides and other compounds that can specifically bind to the c (h) 2-c (h) 3 opening of an immunoglobulin molecule, and methods for using such polypeptides and compounds to inhibit the formation of fc-mediated immunocomplex in viral infection. for example, polypeptides and other compounds can be used to inhibit the binding of immunocomplexed Igg anti-df virion (s) af (y) r, df / dhf / dss infections by inhibiting df a viral antigen binding immunocomplexed igg f (y) re mc1q (membrane c1q) of immunocomplexed igg or soluble c1 binding.
机译:包含多肽的组合物和所述多肽在抑制与病毒感染有关的免疫复合物形成中的用途。可以特异性结合免疫球蛋白分子c(h)2-c(h)3开口的多肽和其他化合物,以及使用这种多肽和化合物抑制病毒感染中fc介导的免疫复合物形成的方法。例如,多肽和其他化合物可用于通过抑制df病毒抗原结合免疫复合物igg f(y)re来抑制免疫复合Igg抗df病毒体与af(y)r,df / dhf / dss感染的结合。免疫复合igg或可溶性c1结合的mc1q(膜c1q)。

著录项

  • 公开/公告号BRPI0915968A2

    专利类型

  • 公开/公告日2020-08-18

    原文格式PDF

  • 申请/专利权人 TRINITY THERAPEUTICS INC;

    申请/专利号BR2009PI15968

  • 发明设计人 NEIL M. BODIE;

    申请日2009-07-17

  • 分类号A61K38/10;A61P31/12;A61P37;

  • 国家 BR

  • 入库时间 2022-08-21 11:18:07

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