首页> 外国专利> A new fragment of human antigen

A new fragment of human antigen

机译:人类抗原的新片段

摘要

A Fab fragment of human antigen is provided, which is expected to be helpful in the diagnosis of cancer, especially rectal cancer, breast cancer, lung cancer, thyroid cancer or the metastatic cancer produced by it. There is also a diagnostic strategy that uses a combination, including magic Shards. The present invention provides a part of Fab anti ceacam5 human antibody, which includes a heavy chain fragment,It includes a variable heavy chain region, which is composed of amino acid sequence, represented by the amino acid position of SEQ No.: 1-121; the light chain includes a variable light chain region, which is composed of amino acid sequence, represented by the position of SEQ 1-112. Ibid., No. 4, and a transposition containing a Fab fragment.
机译:提供了人抗原的Fab片段,其有望有助于癌症的诊断,特别是直肠癌,乳腺癌,肺癌,甲状腺癌或由其产生的转移性癌症。还有一种使用组合的诊断策略,包括魔术碎片。本发明提供了Fab抗ceacam5人抗体的一部分,其包括重链片段,其包括可变重链区,该可变重链区由氨基酸序列组成,由氨基酸序列表示,所述氨基酸序列为1-121。 ;轻链包括由氨基酸序列组成的可变轻链区,由SEQ 1-112的位置表示。同上,第4号,以及含有Fab片段的转座。

著录项

  • 公开/公告号CO2020000517A2

    专利类型

  • 公开/公告日2020-01-31

    原文格式PDF

  • 申请/专利权人 ASTELLAS PHARMA INC.;

    申请/专利号CO20200000517

  • 申请日2020-01-17

  • 分类号C07K16/30;C07K1/13;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/13;C12N15/63;C12P21/08;G01N33/574;

  • 国家 CO

  • 入库时间 2022-08-21 11:18:01

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号