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Hitherto unknown immunotherapy for multiple different tumors, including nerve and brain tumors

机译:迄今未知的针对多种不同肿瘤的免疫疗法,包括神经和脑肿瘤

摘要

The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 25 novel peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
机译:本发明涉及用于免疫治疗方法的肽,核酸和细胞。特别地,本发明涉及癌症的免疫疗法。本发明还涉及单独或与其他肿瘤相关肽组合的肿瘤相关细胞毒性T细胞(CTL)肽表位,其充当刺激抗肿瘤免疫反应的疫苗组合物的活性药物成分。本发明涉及源自人肿瘤细胞的HLA I类和II类分子的25种新的肽序列及其变体,其可用于疫苗组合物中以引发抗肿瘤免疫应答。

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