STABILITIES OF ANTI-CTLA4 ANTIBODIES, SEPARATELY AND IN COMBINATION WITH ANTIBODIES AGAINST PROGRAMMED DEATH RECEPTOR 1 (PD-1), AND METHODS OF APPLICATION

摘要

The invention relates to stable formulations containing antibodies or antigen-binding fragments thereof that bind to cytotoxic T-lymphocyte associated antigen 4 (CTLA4), optionally additionally containing an anti-programmable death receptor 1 antibody (PD-1) or an antigen binding fragment thereof. The present invention also relates to methods for treating various malignant tumors and chronic infections using the compositions of the invention.