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APPLICATION OF CART19 FOR DEPLETING NORMAL B-CELLS FOR TOLERANCE INDUCTION
APPLICATION OF CART19 FOR DEPLETING NORMAL B-CELLS FOR TOLERANCE INDUCTION
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机译:CART19在消除普通B细胞耐受性诱导中的应用
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摘要
The present invention relates to compositions and methods for inducing tolerance in humans. The invention includes the introduction of a genetically modified T cell expressing a CAR, wherein the CAR comprises an antigen binding domain, a transmembrane domain, a co-stimulatory signaling region, and a CD3 zeta signaling domain.
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