3. To suppress APOC3 performance, iarn staff and members

摘要

This note refers to the agents of iarn, such as the double chain agents of iarn, who can inhibit the expression of C-III apoliproteinE gene (also known as APOC3, apoC-III, apoC-III and apo C-III).There are also works by iarn agents from APOC3 The iarn APOC3 agent described in this report can be combined with targeted ligation, including n-ethyl-galactamin ligation, to facilitate cell management, including hepatocytes. It also describes drug components containing one or more iarn APOC3 preparations, with the option of adding one or more therapeutic products. The iarn staff managed the site, and APOC3 provided inhibition of APOC3 gene expression,And it may lead to the decrease of triglyceride level and / or cholesterol level. ICOR APOC3 can be used to treat APOC3 related diseases and diseases, including hypertriglyceridemia, cardiovascular diseases and other related metabolic diseases.