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Polypeptides antagonizing wnt signaling in tumor cells
Polypeptides antagonizing wnt signaling in tumor cells
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机译:拮抗肿瘤细胞中wnt信号转导的多肽
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摘要
The invention provides novel LRP5-binding polypeptides, and more specifically novel LRP5-binding immunoglobulin single variable domain constructs which can inhibit Wnt signaling pathways. The invention also relates to specific sequences of such polypeptides, methods of their production, and methods of using them, including methods of treatment of diseases such as cancer.
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