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Compositions for use in treating or preventing graft-versus host disease or diffuse alveolar hemorrhage or veno-occlusive disease associated with hematopoietic stem cell transplant
Compositions for use in treating or preventing graft-versus host disease or diffuse alveolar hemorrhage or veno-occlusive disease associated with hematopoietic stem cell transplant
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机译:用于治疗或预防与造血干细胞移植相关的移植物抗宿主病或弥漫性肺泡出血或静脉闭塞性疾病的组合物
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摘要
In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a human subject suffering from graft-versus-host disease and/or diffuse alveolar hemorrhage and/or veno-occlusive disease associated with a hematopoietic stem cell transplant. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation.
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