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Synpiii, a promoter for the specific expression of genes in retinal pigment epithelium
Synpiii, a promoter for the specific expression of genes in retinal pigment epithelium
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机译:Synpiii,一种基因在视网膜色素上皮细胞中特异性表达的启动子
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摘要
The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1 or a nucleic acid sequence of at least 1000 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule specifically leads to the expression in cells of the retinal pigment epithelium of a gene when operatively linked to a nucleic acid sequence coding for said gene.
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机译:本发明提供了分离的核酸分子,其包含SEQ ID NO:1的核酸序列或与SEQ ID NO:1的所述序列具有至少80%同一性的至少1000bp的核酸序列或由其组成,其中当与编码所述基因的核酸序列可操作连接时,所述分离的核酸分子特异性地导致该基因在细胞的视网膜色素上皮中表达。
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