3-QUINOLINE CARBOXILIC ACID-1,4,5,6,7,8-HEXAHYDRO-2-METHYL-5-OXO-4-(2-THIENYL) ESTERS AS THE FREE FATTY ACID FAMILY FFAR3 RECEPTOR SELECTIVE LIGANDS AND SYNTONS FOR CREATING NEW LIGANDS

摘要

The invention relates to biochemistry and medicine, in particular to the 3-quinoline carboxilic acid-1,4,5,6,7,8-hexahydro-2-methyl-5-oxo-4-(2-thienyl) esters as the free fatty acid family FFAR3 receptor selective ligands which are useful in medicine for mediating lipid, cholesterol and sugar metabolism, as well as for the normalization and treatment of atherosclerotic processes.