首页> 外国专利> Catena-(µ-nitrato-O,O`-O'')-{methyl-N-(prop-2-en-1-yl)-2-1-(pyridine-2-yl)ethylidenehydrazinecarbimidothioate}copper(II) nitrate compound as superoxide radical inhibitors

Catena-(µ-nitrato-O,O`-O'')-{methyl-N-(prop-2-en-1-yl)-2-1-(pyridine-2-yl)ethylidenehydrazinecarbimidothioate}copper(II) nitrate compound as superoxide radical inhibitors

机译:阳离子-(µ-硝基-O,O`-O'')-{甲基-N-(丙-2-烯-1-基)-2- [1-(吡啶-2-基)亚乙基]肼基碳亚氨基硫代}硝酸铜(II)化合物作为超氧化物自由基抑制剂

摘要

The invention relates to chemistry and medicine, namely to a biologically active coordination compound of copper from the class of transition metal isothiosemicarbazidates. This complex exhibits antiradical activity, inhibiting superoxide radicals in the body. Due to these properties, it can be used in medicine as a drug that prevents the development of cellular and tissue lesions, atherosclerosis and carcinogenesis.According to the invention, claimed is catena-(µ-nitrato-O,O'-O''-{methyl-N-(prop-2-en-1-yl)-2-[1-(pyridine-2-yl)ethylidene]hydrazinecarbimidothioate}copper(II) nitrate compound of the formula:wherein n is limited by the size of the crystal.The said compound expands the arsenal of synthetic superoxide radical inhibitors with high biological activity.
机译:本发明涉及化学和医学,即涉及一种过渡金属异硫代氨基甲酸酯的铜的生物活性配位化合物。该复合物具有抗自由基活性,可抑制体内的超氧自由基。由于这些特性,它可以在医学上用作防止细胞和组织损伤,动脉粥样硬化和致癌作用发展的药物。根据本发明,要求保护的是catena-(μ-nitrato-O,O'-O''式的-{甲基-N-(丙-2-烯-1-基)-2- [1-(吡啶-2-基)亚乙基]肼基碳亚氨基硫代}硝酸铜(II)化合物:该化合物扩大了具有高生物活性的合成超氧化物自由基抑制剂的库。

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