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Pyridin-2-yl-vinylpyridinyl derivatives with fluorescent properties and method of their synthesis

机译:具有荧光性质的吡啶-2-基-乙烯基吡啶基衍生物及其合成方法

摘要

The object of the invention is pyridine-2-yl-vinylpyridinyl derivatives with fluorescent properties and their mode of synthesis. In the first aspect, new derivatives of pyridine-2-yl-vinylpyridinyl, etc., are the subject of the invention. of general formula 3. In the second aspect, the object of the invention is the synthesis of pyridine-2-yl-vinylpyridinyl derivatives of general formula 1 or 2 or 3 or 4 in which the constituents R1, R2, R3, R4, R5 and R6 have the above mentioned meaning. These compounds are used as a fluorescent marker, in particular for the labelling of nucleic acids, nucleosides, nucleotides, peptides or proteins,which can be detached from the labelled biocidal product without damaging or degrading it. These effects cannot be obtained with known fluorescent markers.
机译:本发明的目的是具有荧光性质及其合成方式的吡啶-2-基-乙烯基吡啶基衍生物。在第一方面,吡啶-2-基-乙烯基吡啶基的新衍生物等是本发明的主题。在第二方面,本发明的目的是合成通式1或2或3或4的吡啶-2-基-乙烯基吡啶基衍生物,其中成分R1,R2,R3,R4,R5和R6具有上述含义。这些化合物用作荧光标记物,特别是用于标记核酸,核苷,核苷酸,肽或蛋白质,其可以从标记的杀生物产物上分离而不损坏或降解。使用已知的荧光标记物无法获得这些效果。

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