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Modified amino acid derivatives for treatment of neurological diseases and selected psychiatric disorders

机译:修饰的氨基酸衍生物,用于治疗神经系统疾病和某些精神疾病

摘要

The notified product is a derivative of 2-(2,5-dioxopyrrolidin-1-yl)propanamide with a stereogenic centre configuration selected from: (2R)-N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide of model 1 and (2R)-2-(2,5-dioxopyrrolidin-1-yl)-N-(2-fluorobenzyl)propanamide of model 2. The notification shall also include the following: relationship in the treatment or prevention of epilepsy, epilepsy with associated depressive and anxiety disorders, depression, anxiety, neurological pain, inflammatory pain or neurodegenerative disease.
机译:通报的产品是2-(2,5-二氧杂吡咯烷-1-基)丙酰胺的衍生物,其立体构型中心构型选自:(2R)-N-苄基-2-(2,5-二氧杂吡咯烷-1-基)模型1的丙酰胺和模型2的(2R)-2-(2,5-二氧杂吡咯烷-1-基)-N-(2-氟苄基)丙酰胺。通报还应包括以下内容:在治疗或预防乙肝中的关系癫痫病,伴有抑郁症和焦虑症,抑郁症,焦虑症,神经性疼痛,炎性疼痛或神经退行性疾病的癫痫病。

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