New N-6(4-arylpiperazine-1-yl)hexyl derivatives of cyclic 1,8-naphthyl/tetrahydroquinoline imides/amides/sulfonamides and method of preparing new N-6(4-arylpiperazine-1-yl)hexyl derivatives of cyclic 1,8-naphthyl/tetrahydroquinoline imides/amides/sulfonamides

摘要

N e w N-6(4-arylpiperazin-1-yl)hexyl cyclic derivatives of 1,8-naphthyl / tetrahydroquinoline imides/ amides/ sulfonamides defined in the generic formula (I): where X means N or C; Z means CS, CO or SO2; Y means CO excluding tertahydroquinoline derivatives, or Y means - (empty);n is the length of the alkyl chain from C5 to C8; R is the aryl group defined by the general formula (IA) or (IB) in which: R1, R2, R3 is H, OCH3, OC2H5, Cl, Br, F, CF3, NO2, C3H3N, OCONH, OCH3CONH, C6H5, E, F stands for N or C. These new derivatives of arylpiperazine may be used to treat central nervous system disorders in humans. This notification also revealed how the above new derivatives of arylpiperazine were produced.