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TRANSGENIC PIG ISLETS AND USES THEREOF FOR TREATING DIABETES
TRANSGENIC PIG ISLETS AND USES THEREOF FOR TREATING DIABETES
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机译:转基因猪胰岛及其在糖尿病治疗中的用途
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摘要
The present invention relates to an isolated transgenic pig beta cell wherein the PKC and the PKA pathway are constitutively activated; to a transgenic pig islet comprising said transgenic pig beta cell; and to a transgenic pig comprising said transgenic pig beta cell or said transgenic pig islet. Another object of the invention is a device comprising a transgenic pig beta cell or a transgenic pig islet of the invention. The present invention also relates to the use of said transgenic pig beta cell, said transgenic pig islet, or said device for treating a disease, disorder or condition related to the impaired function of endocrine pancreas or of beta cell.
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