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USE OF VITAMINS AND VITAMIN METABOLIC GENES AND PROTEINS FOR RECOMBINANT PROTEIN PRODUCTION IN MAMMALIAN CELLS
USE OF VITAMINS AND VITAMIN METABOLIC GENES AND PROTEINS FOR RECOMBINANT PROTEIN PRODUCTION IN MAMMALIAN CELLS
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机译:维生素和维生素代谢基因和蛋白质在哺乳动物细胞中重组蛋白生产中的应用
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摘要
Disclosed are eukaryotic expression systems and methods for the selection of mammalian cell lines that produce proteins of interest, such as therapeutic proteins. The systems and methods allow for a simple and fast selection of cells mediating high levels of recombinant protein production. The systems and methods decrease the efforts and time needed to bring a new therapeutic protein to the patients, and also lower the cost of the therapeutic protein by increasing the productivity of cells in a bioreactor.
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