CRYSTALLINE FORM E OF TAFAMIDIS MEGLUMINE, PROCESS FOR PREPARATION AND USE THEREOF

摘要

The present invention discloses a novel crystalline form E of a tafamidis methylglucamine salt, and a preparation method and application thereof. When compared to other known crystalline forms, the new crystalline form provided in the invention has the advantages of easy preparation, low technical requirements, and low hygroscopicity. The invention therefore provides a new and better option for preparing a pharmaceutical product comprising a tafamidis methylglucamine salt, and is very important for pharmaceutical product development.