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TUMOR MARKER, METHYLATION DETECTION REAGENT, KIT AND APPLICATION THEREOF

机译:肿瘤标志物,甲基化检测试剂,试剂盒及其应用

摘要

Disclosed in the present invention are a tumor marker, a methylation detection reagent, a kit and an application thereof. A colorectal cancer specimen may be distinguished from a normal human fecal specimen by means of detecting the methylation level of a TLX2 gene promoter region or jointly detecting the methylation levels of COL4A2 and TLX2 gene promoter regions. The present invention utilizes a methylation detection reagent containing a TLX2 gene or the two genes of COL4A2 and TLX2 to detect colorectal cancer.
机译:本发明公开了一种肿瘤标志物,甲基化检测试剂,试剂盒及其应用。通过检测TLX2基因启动子区域的甲基化水平或共同检测COL4A2和TLX2基因启动子区域的甲基化水平,可以将结肠直肠癌标本与正常人粪便标本区分开。本发明利用含有TLX2基因或COL4A2和TLX2这两个基因的甲基化检测试剂来检测结直肠癌。

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