MALDI-TOF PEPTIDOMIC PROFILE OF FAECES FOR THE DIAGNOSIS OF INTESTINAL INFLAMMATORY DISEASE

摘要

The present invention refer to a diagnostic method based on mass spectrometry, in particular MALDI-TOF/MS, which carried out on a faecal sample previously collected from a subject, allows the diagnosis of an intestinal inflammatory disease. In particular, said method allows to obtain a peptidomic profile that permits diagnosing the presence of a chronic inflammatory bowel disease with high sensitivity and specificity. Said method allows to identify through a single analysis peptidomic profiles able to distinguish healthy persons from ill ones and among the ill ones to distinguish those affected by Crohn's disease of ulcerative rectocolitis.