ANTIMICROBIAL COMPOSITIONS WITH WOUND HEALING PROPERTIES

摘要

Antimicrobial compositions and materials are provided. The compositions include biocompatible material having a synthetic polymer combined with a natural polymer. The combined polymers are crosslinked with an antimicrobial effective amount of a NO-donor. Articles and wound dressings having the biocompatible material are described. Wound dressings can be made by combining a synthetic polymer with a natural polymer to form a polymer mixture and crosslinking the polymer mixture with an antimicrobial effective amount of a NO-donor. The crosslinked polymer mixture can be lyophilized to form a porous film.