首页> 外国专利> DRUG FOR SIMULTANEOUSLY REDUCING RISK OF HAEMORRHAGE AND MICROVASCULAR OBSTRUCTION

DRUG FOR SIMULTANEOUSLY REDUCING RISK OF HAEMORRHAGE AND MICROVASCULAR OBSTRUCTION

机译:药物可同时减少出血和微血管阻塞的风险

摘要

Provided in the present invention is a drug for simultaneously reducing the risk of haemorrhage and microvascular obstruction. Specifically, the present invention provides a composition, the composition comprising (a) a therapeutically effective dose of a first active ingredient, the first active ingredient being clopidogrel or a pharmaceutically acceptable salt thereof; (b) a therapeutically effective dose of a second active ingredient, the second active ingredient being salvianolic acid B or a pharmaceutically acceptable salt thereof; and (c) a therapeutically effective dose of a third active ingredient, the third active ingredient being ginsenoside Rg1 or a pharmaceutically acceptable salt thereof. The first active ingredient, the second active ingredient, and the third active ingredient of the present invention can produce a bilateral synergistic protective effect, effectively reducing microvascular obstruction and effectively preventing haemorrhage, and reducing the dosage of single drugs and reducing drug toxicity.
机译:本发明提供了一种用于同时减少出血和微血管阻塞的风险的药物。具体地,本发明提供了一种组合物,该组合物包含(a)治疗有效剂量的第一活性成分,所述第一活性成分为氯吡格雷或其药学上可接受的盐; (b)治疗有效剂量的第二活性成分,该第二活性成分为丹酚酸B或其药学上可接受的盐; (c)治疗有效剂量的第三活性成分,所述第三活性成分是人参皂苷Rg1或其药学上可接受的盐。本发明的第一活性成分,第二活性成分和第三活性成分可产生双向协同保护作用,有效减少微血管阻塞并有效防止出血,并减少单一药物的剂量并降低药物毒性。

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